About

The hardest problem in health isn't the science. It's getting the science to people.

I'm Garrett Ruhland. I've spent the last decade building companies at that bottleneck: personalized nootropics, a biomarker platform, a decentralized health data network, and now blood-based brain diagnostics.

Email me LinkedIn ↗
Garrett Ruhland in the Grand Tetons
Ventures
2013 TO PRESENT

Different companies, same problem.

2024–PRESENT

Sage Cerebro

CEO NOW

Where I work now, as CEO. We're developing the first blood-based test for neuroinflammation and stroke risk: a six-biomarker panel built on research licensed from UCLA. The underlying science is published in Stroke (2024), which found an 84% increase in stroke risk from baseline elevations in the IL-18 biomarker network. Validation data presented at the International Stroke Conference 2026: 94% specificity against MRI findings. The work is supported by an NIH SBIR grant (R43NS139780). SageSignal launched direct-to-consumer at $499, processed in CLIA-certified labs.

SageSignal kit box
SAGESIGNAL KIT
Six-biomarker panel interface
SIX-BIOMARKER PANEL
Stroke publication behind the panel
STROKE, AHA JOURNALS, 2024
sagecerebro.com ↗
2020–2022

Collab Health

CO-FOUNDER

Co-founder. A decentralized approach to health data: self-sovereign ownership, gamified health quests, and protocol tools for creators. We published a light paper in March 2022; the two demos below show the consumer challenge app and the creator protocol dashboard. We wound it down in 2022: the protocol worked as designed, but there was no realistic base of users who wanted that level of custody over their own health data.

CONSUMER CHALLENGE APP DEMO, 2022 · 0:44

CREATOR PROTOCOL DASHBOARD DEMO, 2022 · 0:51

SYSTEM DESIGN, COLLAB HEALTH, 2021

Light paper, March 2022
2014–2021

Biomarker Labs

CEO

Seven years as CEO, building a personalized health platform: monitoring, recommendations, and e-commerce, built on data from more than 400 devices and sources. We were doing machine learning on personal health data when that still meant building the models yourself. We went through 500 Startups (Batch 20) and raised more than $2M; it wound down in 2021, after a funding round collapsed during COVID.

Garrett pitching Biomarker at 500 Startups Demo Day
ON STAGE AT 500 STARTUPS DEMO DAY, BATCH 20
Biomarker Labs platform dashboard
PLATFORM DASHBOARD, BIOMARKER LABS
2013–2014

truBrain

RESEARCH & DEVELOPMENT

Personalized nootropics. I ran research and development: formulations, and the protocols for measuring whether they actually worked, from a kitchen lab through clinical studies to a shipped product. I left in 2014 to start Biomarker Labs, with the aim of bringing validation to an industry rife with snake oil.

Labeled truBrain think-drink vials
LABELED THINK-DRINK VIALS, 2014
EEG testing session
EEG TESTING, 2014
Expo West badge, Head of Product Development, truBrain
EXPO WEST BADGE, 2014

Along the way I've advised imaware (at-home diagnostics, 2021–2024), Elo Health (personalized nutrition, 2021–2024), and OneFul Health (2023–present).

Origin

At 14, never having had caffeine, I made myself the subject of an experiment: baseline vitals on hospital-grade monitoring, then documentation of what stimulants did to my cardiovascular system. The Orange County Register covered it. My school banned energy drink sales.

I studied molecular biology, neurochemistry, and theatre at Duke. One side taught me how to evaluate evidence. The other taught me how to communicate it.

Orange County Register clipping of the caffeine study
ORANGE COUNTY REGISTER, 2006
Writing

Essays and notes on building health companies: LinkedIn ↗

Otherwise

I'm off the grid somewhere with my wife.

Contact

If you're working on something in health or science, email me.

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